Researchers in Germany develop ‘world’s first’ microrobot with potential for new cancer treatments
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00:00.0
And the heat dissipation, right?
00:01.3
So I think this is a great example
00:02.6
where we have a lot of light colors in focus.
00:05.2
Highest change in signal
00:07.0
due to it being the one that gets heated, right?
00:09.5
And the orange one, this heat is...
00:16.6
Oh, and that one's angry.
00:18.1
I mean, the thing that we're trying...
00:20.5
Not working properly here.
00:21.8
So this is apoptotic behavior, actually.
00:24.5
And we can try and see...
00:26.9
We're using these micro-robots
00:38.7
to build tissues under synthetic conditions.
00:42.7
And the whole point of this is to, in the future,
00:45.1
then repair damaged tissue or organs
00:49.1
at a really patient basis.
00:53.0
So if I can, sort of like, you know,
00:55.2
manufacturing cars in a...
01:00.1
I'm sort of imagining our micro-robots
01:02.3
really picking and placing
01:04.5
very specific types of cells
01:06.5
in a very specific type of architecture
01:10.7
so that we can really tailor that tissue
01:14.9
to the patient's needs.
01:16.7
In this kind of micro-channel?
01:24.1
So this range basically,
01:26.0
we will sometimes...
01:27.7
If we have some, like,
01:38.1
And some others...
01:40.1
I'm interested in just finding out fundamentally
01:43.0
what ticks the cancer cells.
01:46.7
So how can we actually
01:48.2
manipulate their behavior?
01:51.1
That's what I'm trying to find out.
01:53.0
And once we have that information,
01:55.0
then we can use that
01:56.9
to generate better therapies.
02:24.9
And our micro-robots,
02:26.8
are made out of, actually,
02:30.4
We have nanomaterials in there
02:33.0
that allow us to bring functionality
02:35.8
so that we can also
02:37.5
wirelessly control these micro-robots.
02:42.3
they're the same size as the cells,
02:44.7
they're soft as the cells,
02:46.9
and we use them to
02:48.3
communicate with the cells.
02:51.8
Cells that would turn into cancer.
02:55.6
If the robot would...
02:56.5
If the cell is attached to a certain location.
02:58.9
And with this, we have to start off
03:00.9
using these as building blocks
03:02.9
and see how they react.
03:04.9
You can put them all together,
03:05.9
but then, how do they react?
03:06.9
You have to see...
03:12.9
The taxi platform doesn't
03:14.9
immediately help the patients,
03:16.9
but it helps the bioengineers
03:19.9
and the pharmaceutical research
03:23.9
So in that sense,
03:24.9
it's an enabling platform.
03:25.9
It's an enabling technology.
03:27.9
The more we find out about these cells,
03:31.9
The better we can actually design therapeutics.
03:35.9
So this is the one that I put into the data.
03:37.9
And since I'm already here...
03:39.9
This is repeatable, right?
03:41.9
And as soon as the laser is off,
03:43.9
you see this spike?
03:45.9
We have an extremely long time.
03:47.9
So not repeatable.
03:49.9
And then this is where we get the...
03:57.9
we have gold nanoparticles
03:59.9
inside the robots.
04:01.9
And with a laser that we can see here,
04:03.9
we can heat certain areas
04:07.9
And I'll let the video run for a moment,
04:09.9
and then we'll see when we direct the laser
04:11.9
in the direction of the robot,
04:12.9
that it starts to move.
04:13.9
And so we can then move it
04:15.9
within the cell bands
04:17.9
and go to other places,
04:19.9
and then look at several cells
04:21.9
in different ways.
04:25.9
At what temperature do you see the cross talk?
04:36.9
So this response,
04:37.9
I would expect at this temperature,
04:42.9
Did you add some water now?
04:46.9
Normally, do you work in six-well plates?
04:48.9
Or what do you work...
04:49.9
Where do you work?
04:52.9
They also will line more nicely
04:54.9
with less liquid.
04:55.9
They will be more nicely distributed
04:57.9
in the middle and not at the edges.
04:59.9
This is why it's good
